‘Royal blood disorder’ that afflicted Queen Victoria’s family line identified
- SC slams BCCI over Lodha report: Better fall in line, or we will make you fall in line
- SAARC Summit: Now, Bangladesh, Bhutan and Afghanistan say they won't be going to Islamabad
- To isolate Pak, India pulls out of Islamabad SAARC summit
- Global competitiveness index: India jumps 16 ranks for second time, now at 39
- Shimon Peres, last surviving link to Israel's founding fathers, dies at 93
The identity of the 'cursed blood' disorder that troubled the British Royal Family in the 19th and early 20th centuries has been revealed.
DNA analysis show that the disease inherited by Queen Victoria's descendants was probably a severe form of the blood clotting disorder haemophilia B, according to the study published in journal Science.
To reach the conclusion, scientists examined DNA samples extracted from the skeletal remains of Russia's Romanov family and also of Queen Victoria's great grandson Crown Prince Alexei, reports The BBC.
Through analyses, they discovered a mutation in a gene on the X chromosome that codes for the production of Factor IX, a substance that causes blood to clot. This genetic mutation is the cause of haemophilia B.
Since this blood disorder is linked to the X chromosome it passed on through the maternal line, but is only manifested in male descendants.
This is because males have only one X chromosome, so the mutation on that single chromosome is "expressed" as the disease. Females only carry the disease, because their second X chromosome is extremely unlikely to have this same, very rare mutation.
Lead researcher Dr Evgeny Rogaev from the University of Massachusetts told the BBC that it was the "final chapter" in the confirmation of the Romanov family's remains.
- Power struggle within weakens Samajwadi Party already undergoing an identity crisis in UP
- Preventive detention is being routinised as an instrument of state repression
- The challenge of garbage is set to grow, solid waste management plans need to be implemented
- After Uri, a replay of a 2001 predicament
- Any response to Uri must factor in Pakistani state’s relationship with non-state actors
- It is assumed that Blacks will vote 93 per cent for Clinton, seven per cent for Trump