Arunachal Pradesh tribe helps in TB research breakthrough
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From these individuals, the team isolated the CD271+ stem cells, and found evidence of dormant TB bacteria in those stem cells.
These results supported Das's laboratory and Campos-Neto's animal study evidence that dormant TB hide in the CD271+ stem cells, the press statement said.
The findings raise the possibility that other infectious agents may employ similar "wolf-in-stem-cell-clothing" tactics.
And, although any new human treatments are likely to still be years away, they suggest a new possible target in the fight against tuberculosis, which infects nearly 2.2 billion people worldwide.
The study was carried in collaboration with scientists from the Forsyth Institute in Cambridge; Hospital for Sick Children in Toronto; and RIWATCH (Research Institute of World's Ancient Traditions Cultures and Heritage).
Ista Pulu, a Doctor belonging to Idu Mishimi community, and Vijay Swami, Director of RIWATCH are the co-authors of the paper.
Deepjyoti Kalita, a Doctor from Guwahati Medical College who participated in research study and Lab work at Roing is also a co-author from north east India. The study as to "why TB treated patients remain sensitive to TB tests for life" made a breakthrough, "the results now will have direct implications in anti-TBdrug development and explain why it is so difficult to treat active and latent TB" said the RIWATCH release.
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