Cristiano Ronaldo own-goal condemns Madrid to Granada defeat
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Madrid started with plenty of the ball but they were sluggish in their passing and with Granada defending in numbers they were able to close them down without any alarms.
The home side set out their stall to allow Madrid to keep possession in the middle of the pitch while Ronaldo and Angel Di Maria struggled to make any inroads down the wings and they lacked the in-form Mesut Ozil through suspension.
Inigo Lopez headed over for Granada from a corner after 13 minutes and they looked dangerous on several breaks but they lacked a quality final ball.
Eventually Carlos Aranda sent over a telling cross with the Madrid defence stretched after 20 minutes and Alvaro Arbeloa arrived just before Nolito at the far post to knock it behind.
From the resulting corner Granada took the lead as Nolito's cross was flicked into his own net by Ronaldo jumping at the near post.
Madrid offered little in response with shots from distance from Ronaldo and Xabi Alonso.
After the break a 25-yard strike from Ronaldo forced a good save from Tono Rodriguez and they gradually raised the pace of their game in the final half hour.
Substitute Karim Benzema had a glaring miss from a few yards out in the final minutes.
Earlier bottom side Deportivo La Coruna's plight got worse as they lost 3-1 away to Getafe despite going ahead through a Luis Pizzi penalty after eleven minutes and having a man extra with the dismissal of keeper Miguel Moya.
Getafe responded with a penalty of their own through Diego Costa and scored further goals from Alvaro Vazquez and Adrian Colunga while Depor's Abel Aguilar was also sent off in the second half.
Osasuna moved out of the relegation zone with a 1-0 win over Celta Vigo and Espanyol continued their improvement under coach Javier Aguirre with a 3-2 victory over Levante.