PGI comes up wtih computerised system to control anaesthetic delivery

A closed loop anaesthesia delivery system (CLADS) which controls anaesthetic drug delivery automatically based on the feedback of its effect on the patient has been developed at PGI under a project funded by the Department of Information Technology, New Delhi.

The device has also been patented and recently underwent a multicentre evaluation successfully at six different hospitals.

This computer controlled anaesthesia has been used in PGI for open heart surgeries, major non-cardiac surgeries and also in high altitude. This system has been patented in the United States, Europe as well as in India.

Conventionally, anaesthesia is induced using intravenous medicines and thereafter maintained either with anaesthetic gases or intravenous medicines. Dosing of these medicines is based largely on scientific experience and individual patient response to these drugs. The individual patient response is monitored closely by the attending anaesthesiologist to decide fine-tuning of drug dosing.

There could be time delays in display of the monitored value, reading the value, comprehending the change in monitored value and altering the drug delivery manually.

With advances in microprocessor technology, computer control of anaesthesia is an extensively researched area with the idea of supplementing the clinician. CLAD would help save the time spent on adjusting the depth of anaesthesia and enable the clinician to devote his time on other interventions. In addition, automated anaesthesia is not subject to fatigue, thus maintaining the same efficiency throughout a surgical procedure while freeing the physician for more demanding human tasks.

Addressing a press conference on Tuesday, Prof G D Puri said that an advantage of CLAD is that in an operating room, the anaesthesiologist can utilise his attention in looking after other activities like the control of blood pressure and heart rate, doing an echo evaluation of the patient, airway and respiration management.

After proving the utility of the system in a variety of situations within PGI, the investigators decided to test the system at different medical institutions in India.

The project 'Multi-centric Evaluation of Closed Loop Anaesthesia Delivery System' was approved by the Department of Information Technology (DIT) in December 2008.

This was done in six participating centers, including at Sir Ganga Ram Hospital, New Delhi, the Government Medical College and Hospital, Sector 32, Chandigarh, the Dayanand Medical College and Hospital in Ludhiana, SNM Hospital, Leh, GMCH, Patiala and at PGIMER, Chandigarh.

The study was completed in November 2012.

PGI plans to also further other projects to design and develop automated systems for the perioperative and critical care drug delivery in order to fine tune the effects of potent lifesaving drugs during anaesthesia and intensive care.

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