PGI ties with US varsity to tackle prostate cancer

The premier tertiary care institute, PGIMER will soon collaborate with the University of Iowa for various researches, including the one on alpha therapy for prostrate cancer.

Alpha therapy, currently being used in the USA after the successful phase III trials and the recent approval by the FDA, employs new molecules designed to specifically seek out and bind to cancer cells in the body and emit a radioactive particle that can be used to locate disease, as well as selectively kill cancer cells, while leaving healthy cells and tissues intact.

Dr George Weiner, Director, Cancer Centre, University of Iowa and Dr Sudershan Bhatia, Radiation Oncologist who are participating in the three day Second World Congress on Nuclear medicine and are among the pioneers of the technology, said that as per their research, targeted tumour therapy with Alpha Emitters will revolutionise the diagnosis and the treatment of the various types of cancers, starting with prostate cancer.

Speaking to Chandigarh Newsline on the sidelines of the Congress, Dr George Weiner said, "This therapy will significantly reduce the damage caused due to the radiation affecting the other cells in the body."

"In this technique, doctors can target specific cells, which are infected with the radioisotope through alpha emitters mounted on an antibody injected into the patient's body," said Dr Sudershan.

"We hook Alpha with an antibody and each antibody is injected in the patient. These antibodies are organic bodies which carry the Alpha particle directly to the infected part of the cell, without disturbing the other cells surrounding that particular cell," he added

The antibody is chosen according to the metabolism of a patient for maximum compatibility to get positive results.

As of now, in India, the tumours are detected through CT scans, MRIs and Ultrasounds. And for the treatment for the same, Chemotherapy and Beta emitters techniques are being used.

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