Serena Williams defends US Open title, downs Victoria Azarenka in final
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"What a great match and what a great person. Vika is such a great opponent, she's such a great fighter. It was never over until match point," added Williams.
The top seed collected the $2.6 million top prize and pocketed an addition $1 million bonus for having won the U.S. Open run-up series of tournaments.
Azarenka said she had been beaten by the better player.
"It is a tough loss. But the best player deserves the win today. I gave it all again this year," said Azarenka, who lost 7-5 in the third set to Williams in last year's final.
"We gave it everything we got."
In the men's doubles final, Leander Paes and Radek Stepanek were convincing winners over Alexander Peya and Bruno Soares.
The India-Czech pairing of Paes and Stepanek dominated the title match to record a 6-1 6-3 victory over their Austria-Brazil rivals.
Paes, 40, won his third U.S. Open doubles title and eighth major doubles title of his career. It was Stepanek's second major doubles win after claiming the 2012 Australian Open with Paes. Stepanek, 34, said the win enabled them to qualify for an important goal.
"There is one thing we would like to achieve, and that's winning the world championships at the end of the year, because that's the trophy which is missing in Leander's showcase," the Czech said.
Croatia made a clean sweep of the junior singles titles when Borna Coric and Ana Konjuh posted victories at Flushing Meadows. The fourth-seeded Coric beat Australia's Thanasi Kokkinakis 3-6 6-3 6-1 in the boys' final before second-seeded Konjuh beat U.S. wildcard Tornado Black 3-6 6-4 7-6(6).
Coric, 16, said the U.S. Open would be his last junior tournament.
"I've won the slam" he said about his Sunday victory. "That was the goal at the beginning of the year." Coric has been named to Croatia's Davis Cup team for the tie next week against Britain at Umag.